Development of a Computer-Aided Age Determination System: Evaluation Based on Otoliths of Bank Rockfish off California

Author(s):  
Gregor M. Cailliet ◽  
L. W. Botsford ◽  
John G. Brittnacher ◽  
Gary Ford ◽  
M. Matsubayashi ◽  
...  
Terminology ◽  
2021 ◽  
Author(s):  
Oi Yee Kwong

Abstract In this paper, we address the system evaluation issue for commercial term extraction tools from the users’ perspective. We first revisit the gold standard approach commonly practised among researchers, and discuss the challenges it may pose on end users, taking translators as a typical example. Considering the very different motivations and needs of users and researchers, a user-driven approach is proposed as a variation and alternative to the gold standard approach to allow users to assess and understand the performance of commercial tools more objectively. Its feasibility and usefulness are demonstrated by deploying a benchmarking dataset of English-Chinese financial terms, produced by multiple annotators, in a case study with SDL MultiTerm Extract. The results also provide insight for future development of term extractors designed for translators, which will hopefully generate more accurate candidates, offer more customised features, enable better user experience, and enjoy wider popularity as a computer-aided translation tool.


Heart ◽  
1976 ◽  
Vol 38 (12) ◽  
pp. 1247-1261 ◽  
Author(s):  
S Talbot ◽  
L S Dreifus ◽  
Y Watanabe ◽  
R Chiang ◽  
K Morris ◽  
...  

Author(s):  
Mark Ellisman ◽  
Maryann Martone ◽  
Gabriel Soto ◽  
Eleizer Masliah ◽  
David Hessler ◽  
...  

Structurally-oriented biologists examine cells, tissues, organelles and macromolecules in order to gain insight into cellular and molecular physiology by relating structure to function. The understanding of these structures can be greatly enhanced by the use of techniques for the visualization and quantitative analysis of three-dimensional structure. Three projects from current research activities will be presented in order to illustrate both the present capabilities of computer aided techniques as well as their limitations and future possibilities.The first project concerns the three-dimensional reconstruction of the neuritic plaques found in the brains of patients with Alzheimer's disease. We have developed a software package “Synu” for investigation of 3D data sets which has been used in conjunction with laser confocal light microscopy to study the structure of the neuritic plaque. Tissue sections of autopsy samples from patients with Alzheimer's disease were double-labeled for tau, a cytoskeletal marker for abnormal neurites, and synaptophysin, a marker of presynaptic terminals.


Author(s):  
Greg V. Martin ◽  
Ann L. Hubbard

The microtubule (MT) cytoskeleton is necessary for many of the polarized functions of hepatocytes. Among the functions dependent on the MT-based cytoskeleton are polarized secretion of proteins, delivery of endocytosed material to lysosomes, and transcytosis of integral plasma membrane (PM) proteins. Although microtubules have been shown to be crucial to the establishment and maintenance of functional and structural polarization in the hepatocyte, little is known about the architecture of the hepatocyte MT cytoskeleton in vivo, particularly with regard to its relationship to PM domains and membranous organelles. Using an in situ extraction technique that preserves both microtubules and cellular membranes, we have developed a protocol for immunofluorescent co-localization of cytoskeletal elements and integral membrane proteins within 20 µm cryosections of fixed rat liver. Computer-aided 3D reconstruction of multi-spectral confocal microscope images was used to visualize the spatial relationships among the MT cytoskeleton, PM domains and intracellular organelles.


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